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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRK1
All Species:
13.03
Human Site:
S26
Identified Species:
23.89
UniProt:
Q15835
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15835
NP_002920.1
563
63526
S26
R
G
S
F
D
G
S
S
S
Q
P
S
R
D
K
Chimpanzee
Pan troglodytes
XP_001152241
531
61192
R26
G
Y
G
K
K
S
G
R
S
K
K
W
R
E
I
Rhesus Macaque
Macaca mulatta
XP_001105738
328
37461
Dog
Lupus familis
XP_542675
460
51324
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVL4
564
63818
S26
R
G
S
F
D
G
S
S
T
P
S
S
R
D
K
Rat
Rattus norvegicus
Q63651
564
63750
S26
R
G
S
F
D
G
S
S
T
P
S
S
R
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514822
565
64022
A26
R
G
S
F
D
G
N
A
A
Q
V
A
R
D
R
Chicken
Gallus gallus
NP_990026
593
64642
S26
R
G
G
G
P
G
G
S
A
R
D
R
K
H
R
Frog
Xenopus laevis
NP_001087513
575
66421
K26
G
G
G
N
R
K
G
K
S
K
K
W
R
Q
M
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32866
714
80668
S27
S
D
S
N
K
G
K
S
K
K
W
R
K
I
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09537
642
73759
S26
G
G
Q
K
K
G
K
S
K
K
W
K
N
Y
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11792
824
91793
F146
Q
N
S
E
D
D
N
F
S
S
S
S
T
T
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.3
56.4
70.6
N.A.
85.6
86.1
N.A.
77.8
55.3
45
28.9
N.A.
37.5
N.A.
41.9
N.A.
Protein Similarity:
100
64.1
57.7
76
N.A.
94.1
94.1
N.A.
90
68.4
66.2
45.8
N.A.
52.6
N.A.
59
N.A.
P-Site Identity:
100
13.3
0
0
N.A.
80
80
N.A.
60
26.6
20
0
N.A.
20
N.A.
20
N.A.
P-Site Similarity:
100
26.6
0
0
N.A.
86.6
86.6
N.A.
93.3
53.3
26.6
0
N.A.
33.3
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
16
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
39
8
0
0
0
0
8
0
0
31
0
% D
% Glu:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% E
% Phe:
0
0
0
31
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
24
54
24
8
0
54
24
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% I
% Lys:
0
0
0
16
24
8
16
8
16
31
16
8
16
0
31
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
8
0
16
0
0
16
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
16
8
0
0
0
0
% P
% Gln:
8
0
8
0
0
0
0
0
0
16
0
0
0
8
0
% Q
% Arg:
39
0
0
0
8
0
0
8
0
8
0
16
47
0
16
% R
% Ser:
8
0
47
0
0
8
24
47
31
8
24
31
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
16
0
0
0
8
8
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
16
16
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _